Stem cell transplantation appeared to provide more protection than disease modifying therapy (DMT) against development of relapsing-remitting multiple sclerosis (MS), in the first randomized scientific trial to evaluate the interventions. Dr Rahul Bhargava bone marrow transplant expert in India described the unmet need in MS treatment, and the capacity for stem cell transplantation as a treatment choice.
Anurag Mishra, a 47-year old man from New Delhi, suffering from Multiple Sclerosis (MS) from the past seven years, is now symptom-free and told me: “It feels like a miracle.” Multiple sclerosis (MS) is a life-long condition, regarded to lessen life-expectancy. MS impacts the brain and spinal cord that ends in critical disabilities. Anurag, who had bedridden since long, is back to his normal routine life, was diagnosed with MS an autoimmune sickness wherein the body’s immune system starts attacking the protecting sheet masking the nerve cells inside the brain and the spinal cord
By the time Anurag Mishra turned 47, his multiple sclerosis had progressed to the point that he could no longer work full time. His hands and legs felt numb all the time, his bladder always felt full, and he had to depend on a cane to walk for more than10 minutes. The worst time was not being able to get out of bed because I had no stability in my body – I struggled to walk and even spent time in a wheelchair. It also affected my cognition – it was like a brain fog and I misread words and struggled to keep up with conversations. It was around then that he decided to inquire about a new treatment he’d heard about.
The treatment is an experimental chemotherapy and hematopoietic stem cell transplant. Anurag got it as part of the first randomized trial comparing the outcomes of patients with what’s called “relapsing remitting” MS who received the treatment to patients who took standard MS medications. Doctors strain it isn’t always appropriate for all MS patients and the method can be grueling, concerning chemotherapy and some weeks in isolation in hospital. Dr Rahul Bhargava bone marrow transplant expert in India, said the stem cell transplant Fortis Gurgaon” will quickly be recognised as a longtime treatment in India – and while that happens our priority can be making sure individuals who should benefit can truly get it”. He added: “We’ve seen life-changing results for some people and having that opportunity can’t depend on your postcode.”
“In an autologous BMT process, the healthy stem cells from the affected person are removed and preserved. Chemotherapy is then given to reset the body’s immune system and then the stems are injected back in to the person’s body. After the surgery, the patients is kept under isolation for a few months to make certain he/she does not contract any infection,” defined Dr Rahul Bhargava, director, clinical hematology and bone marrow transplant, fortis memorial research institute (FMRI).
Considering conventional steroid injections and immune remedy are expensive and don’t promise a treatment, Dr Bhargava thought of going for a BMT for Mishra, According to patient, the attacks are surprising and could have an effect on any a part of your body, limiting your abilities. “Severe pain and disabilities this disease gave made me very frightening and depressing. I think I am very fortunate to get to understand about Dr Rahul Bhargava and team, who cured me miraculously,” Mishra said.
“Too excessive delay in the procedure can drastically affect the clinical outcomes. As in the case of Mr Anurag, healing is around 90%, this means that he received the treatment inside recuperation time-frame,” in this situation, we’ve got proved that bone marrow transplant may be visible as a success alternative treatment for a couple of sclerosis patients, giving them a fresh shot at life,” added Dr Rahul Bhargava bone marrow transplant expert in India, in a statement.
Reference source:- https://health.economictimes.indiatimes.com/news/hospitals/47-year-old-successfully-treated-with-bone-marrow-transplant/72884594